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Antibiotic consumption in Europe rebounds to pre-pandemic ranges

This 12 months’s European Antibiotic Consciousness Day (EAAD) focuses on the targets outlined within the 2023 Council Advice to step up efforts within the European Union (EU) in opposition to antimicrobial resistance in a One Well being strategy. These suggestions formulate the 2023 purpose to cut back complete antibiotic consumption (neighborhood and hospital sectors mixed) by 20%, utilizing consumption information from 2019 as baseline.

Consumption of antibiotics in the neighborhood accounts for round 90% of the whole use. This implies, {that a} substantial and constant decline in using antibiotics on this sector shall be key on the best way in the direction of reaching the set targets for 2030 which goal at stopping and decreasing antimicrobial resistance total.

Throughout the first 12 months of the COVID-19 pandemic, information from the European Union (EU)/European Financial Space (EEA) confirmed an unprecedented 18.5% lower in neighborhood consumption of antibiotics in 2020 in contrast with the 2019 baseline. This drop has been associated to using non-pharmaceutical interventions (e.g. bodily distancing or carrying of face masks) which lowered total unfold of pathogens, and to the truth that prescriptions of antibiotics have been affected by the disrupted entry to healthcare providers in the course of the first 12 months of the pandemic.

Uncommon fluctuation between 2019 and 2022

Of their fast communication revealed in Eurosurveillance on the event of EAAD and World AMR Consciousness Week, Ventura-Gabarró et al. current most up-to-date information reported to the European Surveillance of Antimicrobial Consumption Community. They present that the noticed lower from 2020 didn’t final.

As a substitute, together with the gradual lifting of interventions throughout the EU/EEA, imply neighborhood consumption went up once more and elevated by 18.8% between 2021 and 2022 with no important distinction from the pre-pandemic degree in 2019. This rebound in consumption of antibacterials for systemic use in the neighborhood sector moved antibiotic consumption charges again in the direction of the 2019 baseline worth.

The information offered by Ventura-Gabarró et al. present totally different patterns of antibiotic consumption throughout the EU/EEA nations. In 13 of 27 nations, neighborhood antibiotic consumption was larger in 2022 than in 2019, with a mean improve of 8.4% amongst these 13 nations (vary: 0.6–26.9).

From 2020 to 2021, the EU/EEA total, as in 15 particular person nations (Austria, Denmark, Estonia, Iceland, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Norway, Portugal, Romania, Slovenia, Spain and Sweden), noticed no or only a marginal (lower than +/−3%) change in antibiotic consumption in the neighborhood. Between 2021 and 2022 pre-pandemic ranges of 2019 have been reached once more with a mean improve of 20.5%.

The authors spotlight that “although the resurgence of both viral and bacterial respiratory tract infections during the latter part of our study period might partly explain this rebound in antibiotic consumption, the increase could also reflect a missed opportunity to strengthen and reinforce prudent antibiotic use.” They conclude that “the COVID-19-pandemic had a substantial impact on community antibiotic consumption in the EU/EEA between 2020 and 2022. Countries exhibited different patterns of antibiotic consumption, underlining the importance of understanding each country in its own context. Further examination into local prescribing and consumption behaviors for specific antibiotic groups can inform effective stewardship interventions and bring the EU/EEA closer to its antibiotic consumption targets for 2030.”

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Journal reference:

Ventura-Gabarró, C., et al. (2023) Rebound in neighborhood antibiotic consumption after the noticed lower in the course of the COVID-19 pandemic, EU/EEA, 2022. Eurosurveillance. doi.org/10.2807/1560-7917.ES.2023.28.46.2300604.

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