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The findings point out that menorrhagia, oligomenorrhea, and polymenorrhea had been the commonest menstrual irregularities after vaccination.

PMID: 

J Infect Public Well being. 2023 Could ;16(5):697-704. Epub 2023 Mar 2. PMID: 36934644

Summary Title: 

COVID-19 vaccination and menstrual problems amongst girls: Findings from a meta-analysis examine.

Summary: 

BACKGROUND: COVID – 19 vaccine can result in numerous native and systemic unwanted side effects, together with menstrual irregularities in girls. There isn’t any sturdy quantitative proof of the affiliation between the COVID – 19 vaccine and menstrual irregularities. A meta-analysis was carried out to estimate the pooled prevalence of a spread of menstrual problems that will happen in girls following COVID – 19 vaccination.METHODS: After trying to find epidemiological research, we systematically carried out a meta-analysis on PubMed/Medline, EMBASE, and Science Direct. Sixteen research had been lastly included within the examine. We estimated the pooled prevalence and corresponding 95 % confidence intervals (CIs) for a bunch of menstrual problems, together with menorrhagia, polymenorrhea, irregular cycle size, and oligomenorrhea. Heterogeneity was assessed utilizing the Istatistic and the Q take a look at.RESULTS: Total, the pooled prevalence of menorrhagia was 24.24 % (pooled prevalence 24.24 %; 95 % CI: 12.8-35.6 %). The pooled prevalence of polymenorrhea was 16.2 % (pooled prevalence: 16.2 %; 95 % CI: 10.7-21.6 %). The pooled prevalence of irregular cycle size was comparatively decrease than that of the opposite problems (pooled prevalence: 6.6 %; 95 % CI: 5.0-8.2 %). The pooled prevalence of oligomenorrhea was 22.7 % (95 % CI: 13.5-32.0 %).CONCLUSION: The findings point out that menorrhagia, oligomenorrhea, and polymenorrhea had been the commonest menstrual irregularities after vaccination. The findings additionally recommend {that a} comparatively excessive proportion of girls undergo from menstrual irregularities. Additional longitudinal research are wanted to substantiate the causal relationship between COVID-19 vaccination and menstrual irregularities.

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