Concentrated pomegranate juice may successfully enhance testosterone ranges in obese and overweight girls with polycystic ovary syndrome.
PMID:
Phytother Res. 2023 Jun ;37(6):2255-2261. Epub 2023 Jan 18. PMID: 36654481
Summary Title:
The impact of concentrated pomegranate juice on biomarkers of irritation, oxidative stress, and intercourse hormones in obese and overweight girls with polycystic ovary syndrome: A randomized managed trial.
Summary:
Polycystic ovary syndrome (PCOS) is a standard gynecological endocrine dysfunction. Pomegranate juice (PJ) has been identified to play anti-inflammatory and antioxidant roles. Nonetheless, the consequences of PJ on irritation, oxidative stress, and intercourse hormones in PCOS sufferers are little or no studied, and thus extra research are wanted. This randomized managed trial enrolled 44 girls recognized with PCOS in response to the Rotterdam standards, physique mass index (BMI) ≥ 25 kg/m, and aged 18-40 years previous. Contributors had been randomly assigned to take 45 ml/day of concentrated PJ or a management group with out intervention. Some biomarkers of intercourse hormones, irritation, and oxidative stress had been quantified at baseline and after the 8-week intervention. In contrast with the controls, serum testosterone ranges had been considerably decreased in obese and overweight girls with PCOS who supplemented with concentrated PJ (-0.004 ± 0.013 vs. 0.039 ± 0.013, p = .039). Nonetheless, we didn’t observe important variations in luteinizing hormone (LH) and intercourse hormone-binding globulin (SHBG) ranges and irritation and oxidative stress elements between the 2 teams after adjustment for confounding variables. An 8-week supplementation with concentrated PJ may successfully enhance testosterone ranges in obese and overweight girls with PCOS. This examine was registered at www.irct.ir (IRCT20191109045383N1).
